China's State Council, the country's cabinet, issued an action plan on Thursday for the continuous improvement of air quality. Under the plan, China should boost the development of new energy and clean energy, while strictly and reasonably controlling coal consumption and prohibiting new steel capacity.
By 2025, it is expected that electricity should account for around 30 percent of total energy end-use consumption, and non-fossil energy consumption should reach around 20 percent, according to the action plan. It was released following the conclusion of the 28th UN Climate Change Conference (COP28) in Dubai last week, during which China's role in global climate governance was highlighted.
The country will also carry out caps on coal consumption while ensuring energy supply security, according to the plan.
It is expected that by 2025, coal consumption in the Beijing-Tianjin-Hebei region and neighboring areas as well as the Yangtze River Delta should drop by 10 percent and 5 percent compared with that of 2020, respectively. And the coal consumption in Fenwei Plain regions in Central China should report negative growth.
In addition to a ban on building new steel factories, Chinese authorities will also resolutely curb the blind launch of high-energy-consuming, high-emission, and low-level projects under the plan.
By 2025, the plan also aims to reduce PM 2.5 concentrations in Chinese cities at and above the prefectural level by 10 percent from 2020, and the annual ratio of days with heavy pollution and above should be within 1 percent. Emissions of nitric oxide and volatile organic compounds (VOCs) should also be reduced by 10 percent from 2020.
The plan marks another effort by China to fulfill its promise of carbon peaking and neutrality. China has committed to a "dual carbon" goal of reaching the peak of carbon emissions by 2030 and attaining carbon neutrality by 2060.
China's actions to address climate change have not only promoted the country's green and low-carbon development, but also made important contributions to addressing global climate change, analysts said.
Lately some customers in Beijing were "shocked" to hear that Daoxiangcun, a store that sells everyday snacks, would no longer be listed as a laozihao, or time-honored brand. Fortunately, it turned out that it was a same-named store in Tianjin, rather than the renowned store in Beijing, that would lose the honor.
Together with the Tianjin Daoxiangcun, 54 other Chinese time-honored brand stores would be removed from the list of Chinese old and famous brands, including Xinluchun restaurant in Beijing, Laobanzhai restaurant in Shanghai, and Guanshengyuan store in Chongqing due to long-term poor operation, bankruptcy or loss of trademarks, according to a recent notice issued by China's Ministry of Commerce (MOC).
China's time-honored brands refer to quality products, excellent techniques or reliable services that have been passed down through generations. With distinctive regional characteristics, most of them have been widely recognized in all sectors over 100 years. In 1991, more than 1,600 businesses were conferred with this title, and in 2006 and 2011, another 1,128 enterprises were added.
According to the MOC, this move aims to improve the protection and inheritance of time-honored brands and build a long-term mechanism for their innovation development, setting well-operated ones as standards and examples for other time-honored brands.
However, some of the brands have lost their advantages due to the changing times, while their standards have fallen.
Tianjin Daoxiangcun, established in 1988, has a reputation for selling high-priced but poor-tasting pastries. Xinluchun restaurant in Beijing used to be well-known in the 1980s for serving savory steamed buns, which some Beijingers still miss. However, after it shifted to regular dishes, its business deteriorated.
Like customers in Beijing, Shanghai residents were also dumbfounded by the removal of the popular and familiar restaurant Laobanzhai. While some expressed regret about the change, others consented saying, "Laobanzhai's environment, services and dishes no longer deserve its status." Some moaned that "short-sighted operators have ruined the business of their ancestors."
Established in 1905, Laobanzhai restaurant serves pastry and Huaiyang cuisine, known for its light and fresh flavor and intricate cooking techniques. It was listed as a time-honored brand in 2006.
To respond to the quality of their services, the manager admitted that a few senior staffers have retired, which "may have caused some problems. But we are trying to improve our services, and at least the quality of the food we serve is guaranteed, and the variety is still popular."
"Now we are striving to reexamine ourselves," the manager said.
While sifting out the unqualified, quite a number of qualified businesses have remained on the list, among which the Daoxiangcun store in Beijing is a good example.
First established in 1895, Beijing Daoxiangcun was the first store to sell dishes from southern China, including pastry, meat and special food for traditional Chinese festivals such as moon cakes as well as frozen food. In 1993, it was listed as a time-honored brand, and in 2004, it won the title of "famous Chinese brand" due to the good quality and reputation of its food and products.
To protect time-honored brands, the list has been increasing instead of decreasing. In August, there were 238 old and famous brands from Beijing on the list with an average age of 140 years, an increase of 15 enterprises , including a traditional Chinese medicine company. Including the Capital Automobile Group, Beijing Tongren Optometry Store and Beijing Ruizhenhou Restaurant, they are part of the eighth batch of businesses on the list and cover more diverse sectors.
Time-honored brands do not just represent the best of the business world, they also have profound cultural significance.
Before a brand was set up, choosing the right name was a major priority as an auspicious name carries the great expectations of the owner of the business.
Normally, owners selected names from famous verses in ancient Chinese literary works such as Dream of Red Mansion to pray for a thriving business, or to show their political aspirations such as jianhua, meaning "building the Chinese nation."
Some entrepreneurs in southern China named their stores with a distinctive local style. A catering business in Suzhou, East China's Jiangsu Province, located in a typical waterside building was named Caizhizhai, or "Collecting Water Lilies." It also serves various, exquisitely made pastries that have been well-received all over the country.
Besides cultural connections, these businesses also uphold customer-centered principles. For instance, each season, Beijing Daoxiangcun will promote different foods to customers and remind them of Chinese traditions.
These time-honored brands represent the best of traditional Chinese culture. Those who have remained on the list demonstrate their success in maintaining the businesses of their ancestors, the continuity of their products and services, and the inheritance of traditional Chinese culture. Those who have vanished must learn to catch up and adapt to the changing times. In this way, they can not only preserve their brands, but also do their bit for the protection of the traditional Chinese culture.
Eggs, long condemned for making raw cookie dough a forbidden pleasure, can stop taking all the blame. There’s another reason to resist the sweet uncooked temptation: flour.
The seemingly innocuous pantry staple can harbor strains of E. coli bacteria that make people sick. And, while not a particularly common source of foodborne illness, flour has been implicated in two E. coli outbreaks in the United States and Canada in the last two years.
Pinning down tainted flour as the source of the U.S. outbreak, which sickened 63 people between December 2015 and September 2016, was trickier than the average food poisoning investigation, researchers recount November 22 in the New England Journal of Medicine. Usually, state health departments rely on standard questionnaires to find a common culprit for a cluster of reported illnesses, says Samuel Crowe, an epidemiologist at the Centers for Disease Control and Prevention in Atlanta, who led the study. But flour isn’t usually tracked on these surveys. So when the initial investigation yielded inconclusive results, public health researchers turned to in-depth personal interviews with 10 people who had fallen ill.
Crowe spent up to two hours asking each person detailed questions about what he or she had eaten around the time of getting sick. Asking people what they ate eight weeks ago can be challenging, Crowe says: Many people can’t even remember what they ate for breakfast that morning.
“I got a little lucky,” Crowe says. Two people remembered eating raw cookie dough before getting sick. They each sent Crowe pictures of the bag of flour they had used to make the batter. It turned out that both bags had been produced in the same plant. That was a “pretty unusual thing,” he says. Follow-up questioning helped Crowe and his team pin down flour as the likely source. Eventually, U.S. Food and Drug Administration scientists analyzed the flour and isolated strains of E. coli bacteria that produce Shiga toxins, which make E. coli dangerous.
Disease-causing bacteria, including E. coli, usually thrive in moist environments, like bags of prewashed lettuce (SN: 12/24/16, p. 4). But the bacteria can also survive in a desiccated state for months and be re-activated with water, says Crowe. So as soon as dry flour mingles with eggs or oil, dormant bacteria can reawaken and start to replicate.
Cookie dough wasn’t the culprit in every case. A few children who got sick had been given raw tortilla dough to play with while waiting for a table at a restaurant. The cases all involved wheat flour from the same facility, leading to a recall of more than 250 flour-containing products.
There are ways to kill bacteria in flour before it reaches grocery store shelves, but they aren’t in use in the United States. Heat treatment, for example, will rid flour of E. coli and other pathogens. But the process also changes the structure of the flour, which affects the texture of baked goods, says Rick Holley, a food safety expert at the University of Manitoba in Canada who wasn’t part of the study. Irradiation, used to kill parasites and other pests in flour, might be a better option, Holley says. But it takes a higher dose of radiation to zap bacteria than it does to kill pests.
Or, of course, people could hold out for warm, freshly baked cookies.
The moon might have formed from the filling during Earth’s jelly doughnut phase.
Around 4.5 billion years ago, something hit Earth, and the moon appeared shortly after. A new simulation of how the moon formed suggests it took shape in the midst of a hot cloud of rotating rock and vapor, which (in theory) forms when big planetary objects smash into each other at high speeds and energies. Planetary scientists Simon Lock of Harvard University and Sarah Stewart of the University of California, Davis proposed this doughnut-shaped planetary blob in 2017 and dubbed it a synestia (SN: 8/5/17, p. 5). Radiation at the surface of this swirling cloud of vaporized, mixed-together planet matter sent rocky rain inward toward bigger debris. The gooey seed of the moon grew from fragments in this hot, high-pressure environment, with a bit of iron solidifying into the lunar core. Some elements, such as potassium and sodium, remained aloft in vapor, accounting for their scarcity in moon rocks today.
After a few hundred years, the synestia shrank and cooled. Eventually, a nearly full-grown moon emerged from the cloud and condensed. While Earth ended up with most of the synestia material, the moon spent enough time in the doughnut filling to gain similar ingredients, Lock, Stewart and colleagues write February 28 in Journal of Geophysical Research: Planets . The simulation shakes up the prevailing explanation for the moon’s birth: A Mars-sized protoplanet called Theia collided with Earth, and the moon formed from distinct rubble pieces. If that’s true, moon rocks should have very different chemical compositions than Earth’s. But they don’t.
Other recent studies have wrestled with why rocks from the moon and Earth are so alike (SN: 4/15/17, p. 18). Having a synestia in the mix shifts the focus from the nature of the collision to what happened in its aftermath, potentially resolving the conundrum.
On the hormonal roller coaster of life, the ups and downs of childbirth are the Tower of Power. For nine long months, a woman’s body and brain absorb a slow upwelling of hormones, notably progesterone and estrogen. The ovaries and placenta produce these two chemicals in a gradual but relentless rise to support the developing fetus.
With the birth of a baby, and the immediate expulsion of the placenta, hormone levels plummet. No other physiological change comes close to this kind of free fall in both speed and intensity. For most women, the brain and body make a smooth landing, but more than 1 in 10 women in the United States may have trouble coping with the sudden crash. Those new mothers are left feeling depressed, isolated or anxious at a time society expects them to be deliriously happy. This has always been so. Mental struggles following childbirth have been recognized for as long as doctors have documented the experience of pregnancy. Hippocrates described a woman’s restlessness and insomnia after giving birth. In the 19th century, some doctors declared that mothers were suffering from “insanity of pregnancy” or “insanity of lactation.” Women were sent to mental hospitals.
Modern medicine recognizes psychiatric suffering in new mothers as an illness like any other, but the condition, known as postpartum depression, still bears stigma. Both depression and anxiety are thought to be woefully underdiagnosed in new mothers, given that many women are afraid to admit that a new baby is anything less than a bundle of joy. It’s not the feeling they expected when they were expecting.
Treatment — when offered — most commonly involves some combination of antidepression medication, hormone therapy, counseling and exercise. Still, a significant number of mothers find these options wanting. Untreated, postpartum depression can last for years, interfering with a mother’s ability to connect with and care for her baby.
Although postpartum depression entered official medical literature in the 1950s, decades have passed with few new options and little research. Even as brain imaging has become a common tool for looking at the innermost workings of the mind, its use to study postpartum depression has been sparse. A 2017 review in Trends in Neurosciences found only 17 human brain imaging studies of postpartum depression completed through 2016. For comparison, more than four times as many have been conducted on a problem called “internet gaming disorder” — an unofficial diagnosis acknowledged only five years ago. Now, however, more researchers are turning their attention to this long-neglected women’s health issue, peering into the brains of women to search for the root causes of the depression. At the same time, animal studies exploring the biochemistry of the postpartum brain are uncovering changes in neural circuitry and areas in need of repair.
And for the first time, researchers are testing an experimental drug designed specifically for postpartum depression. Early results have surprised even the scientists.
Women’s health experts hope that these recent developments signal a new era of research to help new moms who are hurting.
“I get this question all the time: Isn’t it just depression during the postpartum period? My answer is no,” says neuroscientist Benedetta Leuner of Ohio State University. “It’s occurring in the context of dramatic hormonal changes, and that has to be impacting the brain in a unique way. It occurs when you have an infant to care for. There’s no other time in a woman’s life when the stakes are quite as high.”
Brain drain Even though progesterone and estrogen changes create hormonal whiplash, pregnancy wouldn’t be possible without them. Progesterone, largely coming from the ovaries, helps orchestrate a woman’s monthly menstrual cycle. The hormone’s primary job is to help thicken the lining of the uterus so it will warmly welcome a fertilized egg. In months when conception doesn’t happen, progesterone levels fall and the uterine lining disintegrates. If a woman becomes pregnant, the fertilized egg implants in the uterine wall and progesterone production is eventually taken over by the placenta, which acts like an extra endocrine organ.
Like progesterone, estrogen is a normal part of the menstrual cycle that kicks into overdrive after conception. In addition to its usual duties in the female body, estrogen helps encourage the growth of the uterus and fetal development, particularly the formation of the hormone-producing endocrine system.
These surges in estrogen and progesterone, along with other physiological changes, are meant to support the fetus. But the hormones, or chemicals made from them, cross into the mother’s brain, which must constantly adapt. When it doesn’t, signs of trouble can appear even before childbirth, although they are often missed. Despite the name “postpartum,” about half of women who become ill are silently distressed in the later months of pregnancy.
Decades ago, controversy churned over whether postpartum depression was a consequence of fluctuating hormones alone or something else, says neuroscientist Joseph Lonstein of Michigan State University in East Lansing. He studies the neurochemistry of maternal caregiving and postpartum anxiety. Lonstein says many early studies measured hormone levels in women’s blood and tried to determine whether natural fluctuations were associated with the risk of postpartum depression. Those studies found “no clear correlations with [women’s] hormones and their susceptibility to symptoms,” he says. “While the hormone changes are certainly thought to be involved, not all women are equally susceptible. The question then became, what is it about their brains that makes particular women more susceptible?” Seeking answers, researchers have examined rodent brains and placed women into brain scanners to measure the women’s responses to pictures or videos of babies smiling, babbling or crying. Though hormones likely underlie the condition, many investigations have led to the amygdalae. These two, almond-shaped clumps of nerve cells deep in the brain are sometimes referred to as the emotional thermostat for their role in the processing of emotions, particularly fear.
The amygdalae are entangled with many structures that help make mothers feel like mothering, says neuroscientist Alison Fleming of the University of Toronto Mississauga. The amygdalae connect to the striatum, which is involved in experiencing reward, and to the hippocampus, a key player in memory and the body’s stress response. And more: They are wired to the hypothalamus, the interface between the brain and the endocrine system (when you are afraid, the endocrine system produces adrenaline and other chemicals that get your heart racing and palms sweating). The amygdalae are also connected to the prefrontal cortex and insula, involved in decision making, motivation and other functions intertwined with maternal instinct.
Fleming and colleagues have recently moved from studies in postpartum rodents to human mothers. In one investigation, reported in 2012 in Social Neuroscience, women were asked to look at pictures of smiling infants while in a functional MRI, which images brain activity. In mothers who were not depressed, the researchers found a higher amygdala response, more positive feelings and lower stress when women saw their own babies compared with unfamiliar infants.
But an unexpected pattern emerged in mothers with postpartum depression, as the researchers reported in 2016 in Social Neuroscience. While both depressed and not-depressed mothers showed elevated amygdala activity when viewing their own babies, the depressed mothers also showed heightened responses to happy, unknown babies, suggesting reactions to the women’s own children were blunted and not unique. This finding may mean that depressed women had less inclination to emotionally attach to their babies.
Mothers with postpartum depression also showed weaker connectivity between the amygdalae and the insula. Mothers with weaker connectivity in this area had greater symptoms of depression and anxiety. Women with stronger connectivity were more responsive to their newborns.
While there’s still no way to definitely know that the amygdalae are responding to postpartum chemical changes, “it’s very likely,” Lonstein says, pointing out that the amygdalae are influenced by the body’s reaction to hormones in other emotional settings.
Maternal rewards While important, the amygdalae are just part of the puzzle that seems to underlie postpartum depression. Among others is the nucleus accumbens, famous for its role in the brain’s reward system and in addiction, largely driven by the yin and yang of the neurotransmitters dopamine and serotonin. In studies, mothers who watched films of their infants (as opposed to watching unknown infants) experienced increased production of feel-good dopamine. The women also had a strengthening of the connection between the nucleus accumbens, the amygdalae and other structures, researchers from Harvard Medical School and their collaborators reported in February 2017 in Proceedings of the National Academy of Sciences.
That’s not entirely surprising given that rodent mothers find interacting with their newborn pups as neurologically rewarding as addictive drugs, says Ohio State’s Leuner. Rodent mothers that are separated from their offspring “will press a bar 100 times an hour to get to a pup. They will step across electrified grids to get to their pups. They’ve even been shown in some studies to choose the pups over cocaine.” Mothers find their offspring “highly, highly rewarding,” she says.
When there are postpartum glitches in the brain’s reward system, women may find their babies less satisfying, which could increase the risk for impaired mothering. Writing in 2014 in the European Journal of Neuroscience, Leuner and colleagues reported that in rats with symptoms of postpartum depression (induced by stress during pregnancy, a major risk factor for postpartum depression in women), nerve cells in the nucleus accumbens atrophied and showed fewer protrusions called dendritic spines — suggesting weaker connections to surrounding nerve cells compared with healthy rats. This is in contrast to other forms of depression, which show an increase in dendritic spines. Unpublished follow-up experiments conducted by Leuner’s team also point to a role for oxytocin, a hormone that spikes with the birth of a baby as estrogen and progesterone fall. Sometimes called the “cuddle chemical,” oxytocin is known for its role in maternal bonding (SN Online: 4/16/15). Leuner hypothesizes that maternal depression is associated with deficits in oxytocin receptors that enable the hormone to have its effects as part of the brain’s reward system.
If correct, the idea may help explain why oxytocin treatment failed women in some studies of postpartum depression. The hormone may simply not have the same potency in some women whose brains are short on receptors the chemical can latch on to. The next step is to test whether reversing the oxytocin receptor deficits in rodents’ brains relieves symptoms.
Leuner and other scientists emphasize that the oxytocin story is complex. In 2017, in a study reported in Depression & Anxiety, women without a history of depression who received oxytocin — which is often given to promote contractions or stem bleeding after delivery — had a 32 percent higher likelihood of developing postpartum depression than women who did not receive the hormone. In more than 46,000 births, 5 percent of women who did not receive the hormone were diagnosed with depression, compared with 7 percent who did.
“This was the opposite of what we predicted,” says Kristina Deligiannidis, a neuroscientist and perinatal psychiatrist at the Feinstein Institute for Medical Research in Manhasset, N.Y. After all, oxytocin is supposed to enhance brain circuits involved in mothering. “We had a whole group of statisticians reanalyze the data because we didn’t believe it,” she says. While the explanation is unknown, one theory is that perhaps the women who needed synthetic oxytocin during labor weren’t making enough on their own — and that could be why they are more prone to depression after childbirth.
But postpartum depression can’t be pinned to any single substance or brain malfunction — it doesn’t reside in one tidy nest of brain cells, or any one chemical process gone haywire. Maternal behavior is based on complex neurological circuitry. “Multiple parts of the brain are involved in any single function,” Deligiannidis says. “Just to have this conversation, I’m activating several different parts of my brain.” When any kind of depression occurs, she says, multiple regions of the brain are suffering from a communication breakdown.
Looking further, Deligiannidis has also examined the role of certain steroids synthesized from progesterone and other hormones and known to affect maternal brain circuitry. In a 2016 study in Psychoneuroendocrinology involving 32 new mothers at risk for postpartum depression and 24 healthy mothers, Deligiannidis and colleagues reported that concentrations of some steroids that affect the brain, also called neurosteroids, were higher in women at risk for developing depression (because of their past history or symptoms), compared with women who were not. The higher levels suggest a system out of balance — the brain is making too much of one neurosteroid and not enough of another, called allopregnanolone, which is thought to protect against postpartum depression and is being tested as a treatment. Treating pregnancy withdrawal Beyond mom
CASEZY IDEA/SHUTTERSTOCK Postpartum depression doesn’t weigh down just mom. Research suggests it might have negative effects on her offspring that can last for years. Risks include:
Newborns Higher levels of cortisol and other stress hormones More time fussing and crying More “indeterminate sleep,” hovering between deep and active sleep Infants and children Increased risk of developmental problems Slower growth Lower cognitive function Elevated cortisol levels Adolescents Higher risk of depression Tufts University neuroscientist Jamie Maguire, based in Boston, got interested in neurosteroids during her postgraduate studies in the lab of Istvan Mody at UCLA. Maguire and Mody reported in 2008 in Neuron that during pregnancy, the hippocampus has fewer receptors for neurosteroids, presumably to protect the brain from the massive levels of progesterone and estrogen circulating at that time. When progesterone drops after birth, the receptors repopulate.
But in mice genetically engineered to lack those receptors, something else happened: The animals were less interested in tending to their offspring, failing to make nests for them.
“We started investigating. Why are these animals having these abnormal postpartum behaviors?” Maguire recalls. Was an inability to recover these receptors making some women susceptible? Interestingly, similar receptors are responsible for the mood-altering and addictive effects of some antianxiety drugs, suggesting that the sudden progesterone drop after childbirth could be leaving some women with a kind of withdrawal effect.
Further experiments demonstrated that giving the mice a progesterone-derived neurosteroid — producing levels close to what the mice had in pregnancy — alleviated the symptoms.
Today, Maguire is on the scientific advisory board of Boston area–based Sage Therapeutics, which is testing a formulation of allopregnanolone called brexanolone. Results of an early clinical trial published last July in The Lancet assessed whether brexanolone would alleviate postpartum symptoms in women with severe postpartum depression. The study involved 21 women randomly assigned to receive a 60-hour infusion of the drug or a placebo within six months after delivery.
At the end of treatment, the women who received the drug reported a 21-point reduction on a standard scale of depression symptoms, compared with about 9 points for the women on a placebo. “These women got better in about a day,” says Deligiannidis, who is on the study’s research team. “The results were astonishing.”
In November, Sage Therapeutics announced the results of two larger studies, although neither has been published. Combined, the trials involved 226 women with severe or moderate postpartum depression. Both groups showed similar improvements that lasted for the month the women were followed. The company has announced plans to request approval from the U.S. Food and Drug Administration to market brexanolone in the United States. This is an important first step, researchers say, toward better treatments.
“We are just touching on one small piece of a bigger puzzle,” says Jodi Pawluski, a neuroscientist at the Université de Rennes 1 in France who coauthored the 2017 review in Trends in Neurosciences. She was surprised at the dearth of research, given how common postpartum depression is. “This is not the end, it’s the beginning.”
Ask a classroom of children to draw a scientist, and you’ll see plenty of Crayola-colored lab coats, goggles and bubbling beakers. That image hasn’t changed much since the 1960s. But the person wearing the lab coat is shifting.
A new analysis finds that more female scientists have appeared in kids’ drawings in recent decades — going from nearly nonexistent in the 1960s to about a third in 2016.
“A lot has changed since the 1960s,” says David Miller, a Ph.D. candidate in psychology at Northwestern University who reports the findings with colleagues March 20 in Child Development. The first of many “draw-a-scientist” studies asked nearly 5,000 children to draw a scientist between 1966 and 1977. “Of those 5,000 drawings,” Miller says, “only 28 … depicted a female scientist.” That’s just 0.6 percent.
Today, “more women are becoming scientists, and there’s some evidence that female scientists are being represented more in the media,” he says. For instance, in a content analysis of the magazine Highlights for Children, 13 percent of people pictured in science feature stories of the 1960s were women or girls, compared with 44 percent in the 2000s. To look for changes in children’s perceptions over time, the researchers conducted a meta-analysis, combining data from 78 studies that included a total of more than 20,000 U.S. children in kindergarten through 12th grade.
On average, 28 percent of children drew female scientists in studies conducted from 1985 to 2016, the researchers found.
What hasn’t changed much: Kids pick up stereotypes by gender as they grow up. At age 6, girls in the more recent studies drew female scientists about 70 percent of the time. By age 16, 75 percent drew male scientists.
“This is a critical period in which kids are learning stereotypes,” Miller says. “It’s important that teachers and parents present diverse examples of both male and female scientists.”
Editors’ note: This story was corrected on March 21, 2018, to note that by age 16, girls drew only 25 percent of scientists as female.
